Red betel Piper crocatum Latin language, is now present not only as an ornamental plant, but also traditional medicinal plants diabetic (diabetes mellitus - DM).
Community Sleman, Yogyakarta in particular, have taken advantage of properties of red betel leaf is hereditary. Empirically, in addition to diabetes, red betel leaves are often used as an alternative medicine hemorrhoid, inflammation, cancer, gout, hypertension (blood Cleaner), hepatitis, fatigue and ulcers.
Phytochemical compounds contained in red betel leaf that is alkoloid, saponins, tannins, and flavonoids. According to Ivorra, MD in the book "A Review of Natural Products and Plants as Potential antidiabetic," compound
active alkoloid and flavonoids have hypoglycemic activity or lowering blood glucose levels. Hara (1993) states tannins and saponins compounds can be used as an antimicrobial (bacteria and viruses).
Characteristic of this tropical plants, purplish green round trunked and not flowering. The leaves are heart-stemmed form the top and tapering. Leaves the surface shiny and uneven. As betel green, red betel plants also grow vines on the fence or trees. Leaves a bitter taste vibration, but it smelled more fragrant than the green betel. When torn, the red betel leaves slimy.
Red betel plants like the shade, cool and berhawa sun 60-75 percent. Red betel plants flourish and the good in the mountains. When grown in hot areas, direct sunlight, the stem dries quickly. In addition, the red leaves will fade. And Khasiatnya lies in the possibility of chemical compounds contained in red leaves.
Safe to eat
Young researchers from the Institut Pertanian Bogor (IPB), Mega Safithri and Farah have examined Fahma toxicity of water extract of red leaves and its ability to lower blood glucose levels of rats.
Making red betel leaf extract is very easy.
A total of 200 grams of red betel leaves boiled with 1 liter of water until the volume is 100 milliliters lives. Comparison of red betel leaves heavy with boiled extract volume of the drink is 200 grams: 100 milliliters or 2: 1.
To check the security level and the side effects that are antiseptic leaves this, Mega toxicity test. Extracts with concentrations 0, 5, 10, 20 grams per kilogram of body weight given orally to each of the six Sparague dawley rats. After seven days pencekokan, the body weight of mice was increased 24 and healthy wal-alfiat. Means, giving doses of the extract up to 20 grams per kilogram of body weight is safe and not toxic (poisonous).
Appropriate dose as militus diabetes drug, could be determined through testing antihiperglikemik on six groups of rats. Each group consisted of four mice. Group A consists mice received 0.9 per cent NaCl induced weight per volume and cekok akuades. Group B contains aloksan rats induced dose 150 milligrams per kilogram of body weight and cekok akuades.
In the experiment, rats that suffered accidental millitus diabetes, by giving 150 milligrams aloksan dose per kilogram of body weight.
Group C contains aloksan rats induced dose 150 milligrams per kilogram of body weight and antidiabetes drug cekok commercial Daonil 3.22 milligrams per kilogram. Group D, E, F contains aloksan rats induced dose 150 milligrams per kilogram of body weight and cekok consecutive red betel leaf extract 100 x dose Daonil, 1000 x Daonil dose, and 20 grams per kilogram of body weight.
The treatment lasted 10 days. The result, blood glucose level group E and F mice showed no significantly different or the same group of normal mice. Red betel leaf extract dose of 20 grams per kilogram of body weight can reduce blood glucose levels for 34 mice, 3 per cent. Penurunnya higher than anti-diabetes drug delivery militus komesial Daonil 3.22 milligrams per kilogram of which only 27 percent lower blood glucose of rats.
The results of this study can be applied to human diabetics. Dose is the patient weight multiplied by 20 grams per kilogram of body weight. If the patient weight multiplied by degan 20 milligrams per kilogram of body weight. If the patient weight 50 kilograms, he takes 1 kilogram of fresh red betel leaves or 500 ml of boiled water extracts. This can Ektrak taken twice a day every morning and evening as much as 250 ml. However demikina clinical trials in people with diabetes has not been done.
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